Friday Science: Aging, Stem Cells and Stem Cell Niches

I notice that two good review papers on the topic of stem cells, stem cell niches and aging are presently freely available in the latest Aging Cell. Journal publishers tend to put out these free full text promotions for a limited time, so take a look while the looking is there. Stem Cell Review Series: Aging of the skeletal muscle stem cell niche Declining stem cell function during aging contributes to impaired tissue function. Muscle-specific stem cells ('satellite cells') are responsible for generating new muscle in response to injury in the adult. However, aged muscle displays a significant reduction in regenerative abilities and an increased susceptibility to age-related pathologies. This review describes components of the satellite cell niche and addresses how age-related changes in these components impinge on satellite cell function. You can find more about satellite cells and the aging stem cell niche back in the Fight Aging! archives as well. Just follow those links. Stem Cell Review Series: Regulating highly potent stem cells in aging: environmental influences on plasticity Significant advances in the past decade have revealed that a large number of highly plastic stem cells are maintained in humans through adulthood and are present even in older...