did you know it can actually protect your DNA from damage and
mutation? Astounding new evidence supports using creatine for
anti-aging benefits!
A recent study shows that not only does creatine fight muscle
loss, but it can improve brain function and may even help with
inflammation, one systemic cause of aging. In fact, it may also
help with fatigue, muscle atrophy, and even such diseases as
Parkinson's disease or Huntington's disease. It may also help
with brain pathology or mitochondrial disorders.
First, let's take a look at the process of aging. Aging is
caused by oxidants (free radicals) in the body. These molecules
are very unstable and cause reactions and damage with every type
of tissue they come into contact with. As time goes on, the free
radicals cause cellular and DNA damage through the entire body.
Eventually the tissues, of skin, eyes, brain, lungs, liver,
kidneys and virtually every other organ become ineffective and
the organs begin to malfunction. Cancers may also develop due to
the DNA damage from free radicals.
The only way to combat the damage caused by these free radicals
is to introduce anti oxidants into your system though
supplementation and eating fresh healthy foods. These anti
oxidants seek out the free radicals and react with them, turning
them into harmless compounds.
DNA damage is associated with a wide variety of disorders
including cardiovascular disease, a wide variety of tumors
affecting the head, neck, breast, kidney, colon and lungs. In
the study, two dishes containing DNA were exposed to oxidizers
that destroy the DNA and break the molecules down. In one of the
dishes the researchers added creatine. After sitting over night,
they found the DNA without creatine added was almost completely
destroyed. In the dish that contained creatine, the DNA was
almost completely preserved!
After doing much more research, it seems that creatine actually
binds to DNA and destroys the oxidizers as they attempt to
destroy the DNA strands. This is especially good news as it is
very difficult to get most antioxidants to bind to the
mitochondrial DNA.
Creatine is a wonderful supplement as is the most widely used
exercise supplement in the world.
As we age, creatine can be an important part of protecting our
tissues from oxidative damage. Creatine is also very good at
preventing muscle wasting as we age.
Of course, this has benefit to younger adults in that as they
get older, they may not have the muscle wasting their older
peers now suffer from. And of course, because sarcopenia (muscle
wasting) can very possibly be forestalled with creatine
supplementation, it's much easier to prevent it from happening
at all than it is to try to correct it after it does.
In fact, supplementation with as little as five grams of
creatine in 28 healthy adults also involved in resistance
training showed significant improvement in the extension
strength, ankle strength, intramuscular creatine levels, and
strength in general. Of course, what this translates to is that
not only is fat loss stimulated, but this in general leads to
greater strength and flexibility; as we age, we do not have to
lose function and in fact can even gain function with proper
exercise and creatine supplementation.
One possible contraindication is its use in those with kidney
disease. Some have suggested that excessive intake of creatine
can increase levels of creatinine, a byproduct of creatine that
is most often present in those with kidney disease. It is not
known whether creatine itself is harmful in those with kidney
disease and actually affects kidney function, or whether it
simply raises creatinine metabolites.
Nonetheless, for healthy adults, supplementation with up to 5 g
of creatine a day has been shown to have no ill effects
whatsoever thus far. Given its significant benefit, healthy
adults can probably supplement very safely with creatine to
prevent a wide range of aging related issues including DNA
damage and muscle wasting. Used along with a healthy diet and an
exercise program, creatine can be a pillar of your program to
promote long-term health.
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